From: Tissue engineering of skin and regenerative medicine for wound care
Model [references] | Composition | Indications for use |
---|---|---|
Acellular skin substitutes | ||
Bovine collagen and chondroitin-sulfate coated with silicone | Burns, reconstructive surgery | |
Decellularized human dermis | Repair or replacement of damaged or inadequate integumental tissue | |
Bovine collagen and elastin | Burns, reconstructive surgery | |
Derivatized hyaluronic acid | Partial- and full-thickness wounds | |
Bilaminate degradable polyurethane | Burns, reconstructive surgery | |
Temporary skin substitutes (dressings) | ||
Split-thickness skin from human donors, unfrozen or cryopreserved | Burns, reconstructive surgery | |
Split-thickness porcine skin, cryopreserved or lyophilized | Burns, reconstructive surgery | |
Allo hF in collagen gel plus stratified allo hK | Diabetic foot ulcers | |
Allo hF in collagen gel plus stratified allo hK | Partial-thickness burns | |
Allo hF on poly-galactin mesh | Diabetic foot ulcers | |
Permanent skin substitutes (grafts) | ||
Cultured auto hK multi-layer sheet | Full-thickness burns | |
Uncultured suspension of auto hK, delivered as a spray | Partial-thickness burns | |
Auto hF on acellular scaffold of dermal extracelluar matrix, plus stratified auto hK | Full-thickness burns, venous and mixed ulcers | |
Auto hF on a collagen-GAG scaffold, plus stratified auto hK | Full-thickness burns |