From: Quantifying the impact of inhalational burns: a prospective study
Our study SGH Chong | Texas Shirani 1987 [17] | Utah Hollingsed 1993 [18] | North Carolina Smith 1994 [19] | Tokyo Suzuki 2005 [2] | Egypt El-Helbawy 2011 [4] | Taiwan Chen 2014 [1] | USA Anand 2015 [3] | |
---|---|---|---|---|---|---|---|---|
n | 202 | 1058 | 529 | 1447 | 5560 | 281 | 21,791 | 506,628 |
Type of study | Prospective study | Retrospective single centre | Retrospective single centre | Retrospective single centre | Retrospective multicentre | Retrospective single centre | Retrospective multicentre | Retrospective multicentre |
PIB (%) | 17.3 | 35 | 5.7 | 19.6 | 30.4 | 46.3 | 7.9 | 3.47 |
Age (years) | (median) Overall: 42 PIB: 43 PCB: 35 | PCB: 27 Abnormal xenography: 37 Abnormal bronchoscope: 39 | (mean) PIB: 20.2 RF: 36.6 | (mean) Overall: 30 (3 months–93 years) | (mean (SD)) Overall: 40.1 (26.2) PIB: 49.0 (20.5) PCB: 36.2(27.4) | – | (mean(SD)) Overall: 30.9 (22.6) | (mean) Overall: 30 |
%TBSA | (median) Overall: 5 PIB: 5 PCB: 9 | PCB: 23 Abnormal xenography: 37 Abnormal bronchoscope:50 | (mean) PIB: 16.2 RF: 40.4 | (mean)18% (0.4–100%) | mean (SD)) Overall: PIB: 29.9 (30.3) PCB: 16.1 (17.3) | – | mean Overall: 12.2% | – |
Mortality (%) | Overall 3.5 PIB: 17.1 PCB: 0.6 | Overall: 22.7 PIB: 46.6 PCB: 9.6 | Overall: 6.2 PIB -without RF:0 - with RF: 27 PCB: - without RF: 3 - with RF: 50 | Overall 9.5 PIB 31 PCB 4.3 | Overall: 15.8 PIB: 33.6 PCB: 8.1 | Overall: 23.1 PIB: 41.5 PCB: 7.2 | Overall 2.1 PIB: 17.9 PCB: 0.76 | Overall 3.73 PIB: 4× increase in mortality vs PCB |
Length of stay (days) | PIB: 21 PCB: 8 | – | PIB - without RF: 17.8 - with RF: 42.6 PCB - without RF: 15.4 -with RF: 43.2 | – | – | – | – | PIB: 9 PCB: 6 |
Other outcomes | Pneumonia ARDS, AKI infection IV antibiotics, ICU days | Pneumonia PIB: 38% PCB: 8.8% | ARDS PIB: 20% PCB: 2% | – | – | – | Rate of dying due to pneumonia, sepsis and wound infection is higher in PIB | Hospital charges (median) PIB: US$32,070 PCB: US$ 17,600 |