Fig. 1
From: Severe burn injury alters intestinal microbiota composition and impairs intestinal barrier in mice
Severe burn increased intestinal permeability. Intestinal permeability was assessed by measuring fluorescein isothiocyanate-labeled (FITC)-dextran concentration in the systemic circulation after intraluminal injection of 4 kDa FITC-dextran at the indicated time points after 30% total body surface area (TBSA) burn injury. Intestinal permeability to 4 kDa FITC-dextran was significantly increased after burn injury. Data represent the mean ± standard error of the mean (SEM) (n = 5–6). *p < 0.05, ***p < 0.001 compared with 0 h (control), analyzed using Dunnett's t test. Ctrl stands for control group, 1H, 6H stands for 1-h, 6-h post-burn group, 1D, 3D, 5D, 7D stands for 1-day, 3-day, 5-day, 7-day post-burn group