From: Current status of vascularized composite tissue allotransplantation
Achievements | Challenges |
---|---|
Excellent esthetic and functional outcome | Minimization of immunosuppression, tolerance induction |
Multidisciplinary approach | Protocols for sensitized patients |
Recognition as organ, regulated by OPTN | Improved monitoring |
Excellent patient and graft survival | Mechanisms of rejection Acute cellular and humoral rejection |
 | Acute cellular and humoral rejection |
 | Chronic graft deterioration |
 | Nerve regeneration |
 | Definition of acceptable ischemic times |
 | Refined organ preservation |