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Table 2 Methodological characteristics of studies

From: Mannitol cannot reduce the mortality on acute severe traumatic brain injury (TBI) patients: a meta–analyses and systematic review

Author Number of patients Randomization Concealment Blinded Withdraw Single or multicenter Balance of two groups Total modified Jadad score
Vialet et al. [49] 20 Randomization table Envelopes concealment Single Blinded 0 Single center Yes 7/7
Harutjunyan et al. [50] 32 Computer randomly Not reported Not reported 0 Single center Yes 3/7
Francony et al. [51] 17 Randomization table Envelopes concealment Single blinded 0 Multi-center Yes 7/7
Cottenceau et al. [52] 56 Based on blocks of four Envelopes concealment Double blinded 0 Single center Yes 7/7