Skip to main content

Table 6 CPP of included studies

From: Mannitol cannot reduce the mortality on acute severe traumatic brain injury (TBI) patients: a meta–analyses and systematic review

   Measurement of surrogate index Measurement of surrogate index
Number of episodes per day Total duration of episodes, min/day
Vialet et al. [49] Intervention: 20 % M 2 mL/Kg 3.1 ± 3.6**    62 ± 107**  
Control: 7.5 % HSS 2 mL/Kg 4.0 ± 4.6**    58 ± 83**  
   T0 T30 T60 T90 T120
Harutjunyan et al. [50] Intervention: 15 % M 1.4 mL/Kg 61 [47–71] 72 [60–93]* 73 [58–88]*,**   
Control: 7.2 % NaCl/HES 1.8 mL/Kg 60 [39–78] 75 [62–86]*,** 69 [56–89]*   
Cottenceau et al. [52] Intervention: 20 % M 4 mL/Kg 72.1 ± 12.8 76.9 ± 17.48    74.7 ± 13.3*
Control: 7.5 % HSS 2 mL/Kg 72.8 ± 15.1 79.3 ± 11.6*    74.3 ± 13.1*
   Δ% Δ% Δ% Δ% Δ%
Francony et al. [51] Intervention: 20 % M 231 mL 75 ± 15 +21 ± 23* +22 ± 21* +14 ± 15* +17 ± 14*
Control: 7.45 % HSS 100 mL 81 ± 12 +21 ± 23* +9 ± 10* +8 ± 11* +7 ± 6*
  1. *P <0.05 vs. T0; **P <0.05 vs. mannitol