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Table 7 MAP of included studies

From: Mannitol cannot reduce the mortality on acute severe traumatic brain injury (TBI) patients: a meta–analyses and systematic review

   T0 T30 T60 T90 T120
Harutjunyan et al. [50] Intervention: 15 % M 1.4 mL/Kg 84 [68–92] 81 [69–106] 82 [68–108]   
Control: 7.2 % NaCl/HES 1.8 mL/Kg 84 [64–98] 85 [74–100]*,** 84 [63–94]*   
Cottenceau et al. [52] Intervention: 20 %M 4 mL/Kg 87.6 ± 12.2 87.4 ± 11.6    87.9 ± 10.9
Control: 7.5 % HSS 2 mL/Kg 90.6 ± 12.6 91.2 ± 10    87.2 ± 10.5
   Δ% Δ% Δ% Δ% Δ%
Francony et al. [51] Intervention: 20 % M 231 mL 106 ± 16 +2 ± 9 +1 ± 10 0 ± 10* +2 ± 7
Control: 7.45 %Hss 100 mL 108 ± 13 −5 ± 7 −2 ± 7 −3 ± 7* −1 ± 5
  1. *P <0.05 vs. T0; **P <0.05 vs. mannitol