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Table 8 Plasma osmolality and serum sodium of included studies

From: Mannitol cannot reduce the mortality on acute severe traumatic brain injury (TBI) patients: a meta–analyses and systematic review

  Measurement of surrogate index Intervention Control
Vialet et al. [49] Serum sodium (Δ%)   +1.3 ± 10.1* +4.7 ± 8.2*
Francony et al. [51] Serum sodium (Δ%)   −1.7 ± 3.2** +2.1 ± 1.4**
Urine output (mL/h)   306 ± 174** 114 ± 72**
Harutjunyan et al. [50] Serum sodium T0   143 (136–148)
T30   148 (144–153)*
Plasma T0 286 (270–315)* 284 (273–300)*
Osmolality T30 295 (278–327)* 300 (284–319)*
Cottenceau et al. [52] Serum sodium T0 141.3 ± 5.1 144.2 ± 5.1
T30 139.1 ± 4.1*,** 148.3 ± 5.2*,**
  1. *P <0.05 vs. T0; **P <0.05 vs. mannitol