From: Vitamin D deficiency in critically ill patients with traumatic injuries
Variable | Normal | Insufficient | Deficient | Severely deficient | P ≤ |
---|---|---|---|---|---|
25-OH vitamin D concentration range, ng/mL | 30–80 | 20–29.9 | 13.1–19.9 | ≤13 |  |
N | 6 | 31 | 75 | 46 | Â |
Male/female, n/n | 5/1 | 27/4 | 61/14 | 37/9 | 0.885 |
Race | Â | Â | Â | Â | Â |
 Caucasian, n (%) | 5 (83 %) | 22 (71 %) | 34 (45 %) | 13 (28 %) | 0.004 |
 African-American, n (%) | 1 (17 %) | 5 (16 %) | 32 (43 %) | 27 (59 %) |  |
 Hispanic/other, n (%) | 0 (0 %) | 4 (13 %) | 9 (12 %) | 6 (13 %) |  |
Etiology for admission | Â | Â | Â | Â | Â |
 MVA, n (%) | 1 (17 %) | 21 (68 %) | 48 (64 %) | 18 (39 %) | 0.001 |
 GSW/KSW, n (%) | 0 (0 %) | 1 (3 %) | 14 (19 %) | 19 (41 %) |  |
 Fall/Assault, n (%) | 5 (83 %) | 6 (19 %) | 9 (12 %) | 6 (13 %) |  |
 Other, n (%) | 0 (0 %) | 3 (10 %) | 4 (5 %) | 3 (7 %) |  |
Age, years | 60 ± 30 | 46 ± 22 | 45 ± 18 | 43 ± 17 | 0.243 |
Weight, kg | 70 ± 20 | 85 ± 17 | 88 ± 23 | 87 ± 19 | 0.206 |
BMI, kg/m2 | 22 ± 5 | 27 ± 4 | 28 ± 7 | 29 ± 5 | 0.033 |
Injury severity score | 25 ± 6 | 30 ± 14 | 27 ± 14 | 29 ± 13 | 0.399 |
C-reactive protein, mg/dL | 20.4 ± 12.0 | 18.5 ± 12.0 | 22.1 ± 12.5 | 23.7 ± 11.9 | 0.380 |
Prealbumin, mg/dL | 8.9 ± 5.6 | 9.9 ± 8.2 | 8.7 ± 4.1 | 8.5 ± 3.7 | 0.989 |
Alcohol abuse, n (%) | 1 (17Â %) | 10 (32Â %) | 17 (23Â %) | 12 (26Â %) | 0.720 |
Admitted Nov–Mar, n (%) | 3 (50 %) | 10 (32 %) | 29 (39 %) | 24 (52 %) | 0.300 |
Serum ionized calcium, mmol/L | 1.19 ± 0.06 | 1.17 ± 0.06 | 1.18 ± 0.09 | 1.16 ± 0.07 | 0.407 |
Serum phosphorus, mg/dL | 2.9 ± 0.3 | 3.8 ± 0.8 | 3.6 ± 1.0 | 3.6 ± 1.0 | 0.055 |
25-OH vitamin D, ng/mL | 39.2 ± 7.3 | 23.2 ± 3.0 | 16.0 ± 2.2 | 12.8 ± 0.5 | 0.001 |
Hospital day of vitamin D determination, days | 6.2 ± 2.9 | 9.8 ± 5.6 | 7.4 ± 5.3 | 7.1 ± 4.5 | 0.077 |