Fig. 1From: Tissue engineering of skin and regenerative medicine for wound careClinical application of autologous engineered skin substitutes (ESS). a Histology of ESS shows a collagen-based polymer scaffold populated with cultured dermal fibroblasts and epidermal keratinocytes. Scale bar = 0.1 mm. b Surgical application of ESS on prepared wounds can be performed using forceps and secured with staples. c An African-American subject treated with ESS at 3 years of age shows predominant hypopigmentation. d The same subject at 14 years of age has persistent hypopigmentation but has required no reconstruction of the ESS site. Scales in centimetersBack to article page