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Table 5 Adjusted odds ratios of complications in patients with inhalational injury using logistic regression analysis

From: Quantifying the impact of inhalational burns: a prospective study

 

Inhalational injury

Inhalational injury, adjusted for %TBSA

Inhalational injury, adjusted for %TBSA and age (except %TBSA, adjusted for age only)

OR

95% CI

p value

Adjusted OR

95% CI

p value

Adjusted OR

95% CI

p value

%TBSA > median, 5

1.78

0.82–3.87

0.146

1.66

0.76–3.64

0.204

Age > median, 42 (years)

0.60

0.29–1.26

0.175

0.71

0.31–1.62

0.414

All complications

8.33

3.62–19.17

< 0.001

5.31

2.17–12.98

< 0.001

6.27

2.49–15.77

< 0.001

Intubation

68.96

20.65–230.3

< 0.001

67.19

12.47–361.89

< 0.001

86.99

14.22–544.43

< 0.001

Pneumonia

48.75

10.30–230.55

< 0.001

13.87

2.32–82.94

0.004

35.51

3.90–323.07

0.002

ARDS

156.78

19.69–1248.17

< 0.001

106.71

12.73–894.53

< 0.001

480.70

28.47–8115.89

< 0.001

AKI

48.75

10.31–230.55

< 0.001

17.43

3.07–98.87

< 0.001

31.71

4.38–229.7

0.001

Bacteraemia

18.68

5.50–63.39

< 0.001

2.39

0.38–15.04

NS

2.56

0.40–16.57

NS

Burn wound infection

3.15

1.49–6.67

0.003

1.28

0.49–3.35

NS

1.35

0.52–3.54

NS

Mortality

34.35

3.99–295.86

0.001

0.38

0.01–11.29

NS

0.60

0.01–44.53

NS

HD admission

20.39

6.82–60.95

< 0.001

15.70

4.87–50.62

< 0.001

15.55

4.82–50.20

< 0.001

ICU admission

26.57

10.41–67.90

< 0.001

16.26

5.23–50.57

< 0.001

16.63

5.28–52.34

< 0.001

Number of surgery sessions > median, 1

0.53

0.24–1.16

0.111

0.22

0.08–0.64

0.005

0.21

0.07–0.62

0.004

Length of stay > median, 8.5

1.89

0.89–3.99

0.098

1.05

0.44–2.47

0.915

1.12

0.47–2.67

0.797

Days on IV antibiotics > median, 4

1.71

0.81–3.63

0.160

0.84

0.35–2.04

0.699

0.86

0.36–2.11

0.749

Days of mechanical ventilation > median 2.5

41.00

10.91–154.04

< 0.001

11.94

2.34–60.8

0.003

18.38

2.97–113.682

0.002

Initial P/F ratio < median 394.02

36.45

9.67–137.40

< 0.001

28.89

7.02–118.89

< 0.001

44.85

9.10–221.13

< 0.001

Lowest P/F ratio in 2 days < median, 343.88

124.50

15.61–993.29

< 0.001

78.88

9.28–670.76

< 0.001

140.58

13.14–1504.25

< 0.001

Lowest P/F ratio in 1 week < 300

156.78

19.69–1248.17

< 0.001

106.72

12.73–894.54

< 0.001

480.70

28.47–8115.89

< 0.001

  1. OR odds ratio, CI confidence interval, NS non-significant, ARDS acute respiratory distress syndrome, AKI acute kidney injury, IV intravenous, RF respiratory failure, ICU intensive care unit, HD high dependency unit, %TBSA percentage of total body surface area, SD standard deviation, CI confidence interval, P/F PaO2 /FiO2