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Table 5 Adjusted odds ratios of complications in patients with inhalational injury using logistic regression analysis

From: Quantifying the impact of inhalational burns: a prospective study

  Inhalational injury Inhalational injury, adjusted for %TBSA Inhalational injury, adjusted for %TBSA and age (except %TBSA, adjusted for age only)
OR 95% CI p value Adjusted OR 95% CI p value Adjusted OR 95% CI p value
%TBSA > median, 5 1.78 0.82–3.87 0.146 1.66 0.76–3.64 0.204
Age > median, 42 (years) 0.60 0.29–1.26 0.175 0.71 0.31–1.62 0.414
All complications 8.33 3.62–19.17 < 0.001 5.31 2.17–12.98 < 0.001 6.27 2.49–15.77 < 0.001
Intubation 68.96 20.65–230.3 < 0.001 67.19 12.47–361.89 < 0.001 86.99 14.22–544.43 < 0.001
Pneumonia 48.75 10.30–230.55 < 0.001 13.87 2.32–82.94 0.004 35.51 3.90–323.07 0.002
ARDS 156.78 19.69–1248.17 < 0.001 106.71 12.73–894.53 < 0.001 480.70 28.47–8115.89 < 0.001
AKI 48.75 10.31–230.55 < 0.001 17.43 3.07–98.87 < 0.001 31.71 4.38–229.7 0.001
Bacteraemia 18.68 5.50–63.39 < 0.001 2.39 0.38–15.04 NS 2.56 0.40–16.57 NS
Burn wound infection 3.15 1.49–6.67 0.003 1.28 0.49–3.35 NS 1.35 0.52–3.54 NS
Mortality 34.35 3.99–295.86 0.001 0.38 0.01–11.29 NS 0.60 0.01–44.53 NS
HD admission 20.39 6.82–60.95 < 0.001 15.70 4.87–50.62 < 0.001 15.55 4.82–50.20 < 0.001
ICU admission 26.57 10.41–67.90 < 0.001 16.26 5.23–50.57 < 0.001 16.63 5.28–52.34 < 0.001
Number of surgery sessions > median, 1 0.53 0.24–1.16 0.111 0.22 0.08–0.64 0.005 0.21 0.07–0.62 0.004
Length of stay > median, 8.5 1.89 0.89–3.99 0.098 1.05 0.44–2.47 0.915 1.12 0.47–2.67 0.797
Days on IV antibiotics > median, 4 1.71 0.81–3.63 0.160 0.84 0.35–2.04 0.699 0.86 0.36–2.11 0.749
Days of mechanical ventilation > median 2.5 41.00 10.91–154.04 < 0.001 11.94 2.34–60.8 0.003 18.38 2.97–113.682 0.002
Initial P/F ratio < median 394.02 36.45 9.67–137.40 < 0.001 28.89 7.02–118.89 < 0.001 44.85 9.10–221.13 < 0.001
Lowest P/F ratio in 2 days < median, 343.88 124.50 15.61–993.29 < 0.001 78.88 9.28–670.76 < 0.001 140.58 13.14–1504.25 < 0.001
Lowest P/F ratio in 1 week < 300 156.78 19.69–1248.17 < 0.001 106.72 12.73–894.54 < 0.001 480.70 28.47–8115.89 < 0.001
  1. OR odds ratio, CI confidence interval, NS non-significant, ARDS acute respiratory distress syndrome, AKI acute kidney injury, IV intravenous, RF respiratory failure, ICU intensive care unit, HD high dependency unit, %TBSA percentage of total body surface area, SD standard deviation, CI confidence interval, P/F PaO2 /FiO2