From: Quantifying the impact of inhalational burns: a prospective study
Inhalational injury | Inhalational injury, adjusted for %TBSA | Inhalational injury, adjusted for %TBSA and age (except %TBSA, adjusted for age only) | |||||||
---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p value | Adjusted OR | 95% CI | p value | Adjusted OR | 95% CI | p value | |
%TBSA > median, 5 | 1.78 | 0.82–3.87 | 0.146 | – | – | – | 1.66 | 0.76–3.64 | 0.204 |
Age > median, 42 (years) | 0.60 | 0.29–1.26 | 0.175 | 0.71 | 0.31–1.62 | 0.414 | – | – | – |
All complications | 8.33 | 3.62–19.17 | < 0.001 | 5.31 | 2.17–12.98 | < 0.001 | 6.27 | 2.49–15.77 | < 0.001 |
Intubation | 68.96 | 20.65–230.3 | < 0.001 | 67.19 | 12.47–361.89 | < 0.001 | 86.99 | 14.22–544.43 | < 0.001 |
Pneumonia | 48.75 | 10.30–230.55 | < 0.001 | 13.87 | 2.32–82.94 | 0.004 | 35.51 | 3.90–323.07 | 0.002 |
ARDS | 156.78 | 19.69–1248.17 | < 0.001 | 106.71 | 12.73–894.53 | < 0.001 | 480.70 | 28.47–8115.89 | < 0.001 |
AKI | 48.75 | 10.31–230.55 | < 0.001 | 17.43 | 3.07–98.87 | < 0.001 | 31.71 | 4.38–229.7 | 0.001 |
Bacteraemia | 18.68 | 5.50–63.39 | < 0.001 | 2.39 | 0.38–15.04 | NS | 2.56 | 0.40–16.57 | NS |
Burn wound infection | 3.15 | 1.49–6.67 | 0.003 | 1.28 | 0.49–3.35 | NS | 1.35 | 0.52–3.54 | NS |
Mortality | 34.35 | 3.99–295.86 | 0.001 | 0.38 | 0.01–11.29 | NS | 0.60 | 0.01–44.53 | NS |
HD admission | 20.39 | 6.82–60.95 | < 0.001 | 15.70 | 4.87–50.62 | < 0.001 | 15.55 | 4.82–50.20 | < 0.001 |
ICU admission | 26.57 | 10.41–67.90 | < 0.001 | 16.26 | 5.23–50.57 | < 0.001 | 16.63 | 5.28–52.34 | < 0.001 |
Number of surgery sessions > median, 1 | 0.53 | 0.24–1.16 | 0.111 | 0.22 | 0.08–0.64 | 0.005 | 0.21 | 0.07–0.62 | 0.004 |
Length of stay > median, 8.5 | 1.89 | 0.89–3.99 | 0.098 | 1.05 | 0.44–2.47 | 0.915 | 1.12 | 0.47–2.67 | 0.797 |
Days on IV antibiotics > median, 4 | 1.71 | 0.81–3.63 | 0.160 | 0.84 | 0.35–2.04 | 0.699 | 0.86 | 0.36–2.11 | 0.749 |
Days of mechanical ventilation > median 2.5 | 41.00 | 10.91–154.04 | < 0.001 | 11.94 | 2.34–60.8 | 0.003 | 18.38 | 2.97–113.682 | 0.002 |
Initial P/F ratio < median 394.02 | 36.45 | 9.67–137.40 | < 0.001 | 28.89 | 7.02–118.89 | < 0.001 | 44.85 | 9.10–221.13 | < 0.001 |
Lowest P/F ratio in 2 days < median, 343.88 | 124.50 | 15.61–993.29 | < 0.001 | 78.88 | 9.28–670.76 | < 0.001 | 140.58 | 13.14–1504.25 | < 0.001 |
Lowest P/F ratio in 1 week < 300 | 156.78 | 19.69–1248.17 | < 0.001 | 106.72 | 12.73–894.54 | < 0.001 | 480.70 | 28.47–8115.89 | < 0.001 |