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Table 6 Retrospective studies on inhalational injury, mortality, length of stay and other clinical outcomes

From: Quantifying the impact of inhalational burns: a prospective study

 

Our study SGH Chong

Texas

Shirani 1987 [17]

Utah

Hollingsed 1993 [18]

North Carolina

Smith 1994 [19]

Tokyo

Suzuki 2005 [2]

Egypt

El-Helbawy 2011 [4]

Taiwan

Chen 2014 [1]

USA

Anand 2015 [3]

n

202

1058

529

1447

5560

281

21,791

506,628

Type of study

Prospective study

Retrospective single centre

Retrospective single centre

Retrospective single centre

Retrospective multicentre

Retrospective single centre

Retrospective multicentre

Retrospective multicentre

PIB (%)

17.3

35

5.7

19.6

30.4

46.3

7.9

3.47

Age (years)

(median)

Overall: 42

PIB: 43

PCB: 35

PCB: 27 Abnormal xenography: 37

Abnormal bronchoscope: 39

(mean)

PIB: 20.2

RF: 36.6

(mean)

Overall: 30 (3 months–93 years)

(mean (SD))

Overall: 40.1 (26.2)

PIB: 49.0 (20.5) PCB: 36.2(27.4)

(mean(SD))

Overall: 30.9 (22.6)

(mean) Overall: 30

%TBSA

(median)

Overall: 5

PIB: 5

PCB: 9

PCB: 23

Abnormal xenography: 37

Abnormal bronchoscope:50

(mean)

PIB: 16.2

RF: 40.4

(mean)18% (0.4–100%)

mean (SD))

Overall: PIB: 29.9 (30.3)

PCB: 16.1 (17.3)

mean Overall: 12.2%

Mortality (%)

Overall 3.5

PIB: 17.1

PCB: 0.6

Overall: 22.7

PIB: 46.6

PCB: 9.6

Overall: 6.2

PIB -without RF:0

- with RF: 27

PCB:

- without RF: 3

- with RF: 50

Overall 9.5

PIB 31

PCB 4.3

Overall: 15.8

PIB: 33.6

PCB: 8.1

Overall: 23.1

PIB: 41.5

PCB: 7.2

Overall 2.1

PIB: 17.9

PCB: 0.76

Overall 3.73

PIB: 4× increase in mortality vs PCB

Length of stay (days)

PIB: 21

PCB: 8

PIB

- without RF: 17.8

- with RF: 42.6

PCB

- without RF: 15.4

-with RF: 43.2

PIB: 9

PCB: 6

Other outcomes

Pneumonia

ARDS, AKI

infection

IV antibiotics, ICU days

Pneumonia

PIB: 38%

PCB: 8.8%

ARDS

PIB: 20%

PCB: 2%

Rate of dying due to pneumonia, sepsis and wound infection is higher in PIB

Hospital charges (median)

PIB: US$32,070

PCB: US$ 17,600

  1. PIB patients with inhalational burns, PCB patients with only cutaneous burns, ARDS acute respiratory distress syndrome, AKI acute kidney injury, IV intravenous, RF respiratory failure, ICU intensive care unit, %TBSA percentage of total body surface area, SD standard deviation