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Table 1 Summary of ocular and peri-ocular burns studies included in systematic review and meta-analysis

From: Acute surgical vs non-surgical management for ocular and peri-ocular burns: a systematic review and meta-analysis

AuthorYearDesignSample sizeEtiologyGroup characteristicsBurn classificationOutcomesComplications
Frank et al. [15]1983Retrospective cohort92• –• Eyelid surgery
• Eyelid no surgery
• DPT
• FT
• –• Corneal ulceration
• Vision loss
• Ectropian
• Eye perforation
Tamhane et al. [16]2005Prospective, randomized trial44• Thermal
• Acid
• Alkali
• Eye surgery
• Eye no surgery
• Dua’s grade II-VI• Visual acuity
• Pain
• Epithelial defect area
• Schirmer
• TBUT
• Wound/ocular infection
• Symblepharon
• Corneal vascularization
Lopez-Garcia et al. [17]2006Prospective cohort24• Alkali• Eye surgery
• Eye no surgery
• Dua’s grade III, IV• Visual acuity• Corneal ulceration
• Corneal vascularization
Singh et al. [18]2008Retrospective cohort100• Acid
• Alkali
• Chemical
• Eye surgery
• Eye no surgery
• Dua’s grade II-VI• Visual acuity
• Corneal haze
• Symblepharon
• Corneal vascularization
Tandon et al. [19]2011Prospective, randomized trial153• Thermal
• Acid
• Alkali
• Eyelid surgery
• Eyelid no surgery
• Eye surgery
• Eye no surgery
• Dua’s grade II, III• Time to management
• Visual acuity
• Corneal haze
• Epithelial defect area
• Time to epithelialization
• Limbal ischemia
• Symblepharon
• Corneal vascularization
Sharma et al. [20]2015Retrospective cohort28• Acid
• Alkali
• Eye surgery
• Eye no surgery
• Dua’s grade III-V• Time to management
• Visual acuity
• Corneal haze
• Epithelial defect diameter
• Epithelial defect area
• Schirmer
• TBUT
• Time to epithelialization
• Healed epithelial defect
• Symblepharon
• Entropian
• Ectropian
• Corneal vascularization
Sharma et al. [21]2016Prospective, randomized trial30• Acid
• Alkali
• Eye surgery
• Eye no surgery
• Dua’s grade III-V• Time to management
• Pain
• Corneal haze
• Epithelial defect diameter
• Epithelial defect area
• Schirmer
• TBUT
• Time to epithelialization
• Healed epithelial defect
• Limbal ischemia
• Symblepharon
• Corneal vascularization
Cabalag et al. [2]2017Retrospective cohort326• Thermal
• Chemical
• Eyelid surgery
• Eyelid no surgery
• Eye surgery
• Eye no surgery
• Eyelash surgery
• Eyelash no surgery
• SPT
• DPT
• FT
• Dua’s grade I, II
• %TBSA
• Time to management
• LOS
• Rate of intubation
• Inhalation injury
• Wound/ocular infection
• Eyelid contracture
• Corneal ulceration
• Vision loss
• Ectropian
  1. SPT superficial partial thickness, DPT deep partial thickness, FT full thickness, TBUT tear break-up time, LOS length of stay, %TBSA percent total body surface area