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Table 1 Summary of ocular and peri-ocular burns studies included in systematic review and meta-analysis

From: Acute surgical vs non-surgical management for ocular and peri-ocular burns: a systematic review and meta-analysis

Author

Year

Design

Sample size

Etiology

Group characteristics

Burn classification

Outcomes

Complications

Frank et al. [15]

1983

Retrospective cohort

92

• –

• Eyelid surgery

• Eyelid no surgery

• DPT

• FT

• –

• Corneal ulceration

• Vision loss

• Ectropian

• Eye perforation

Tamhane et al. [16]

2005

Prospective, randomized trial

44

• Thermal

• Acid

• Alkali

• Eye surgery

• Eye no surgery

• Dua’s grade II-VI

• Visual acuity

• Pain

• Epithelial defect area

• Schirmer

• TBUT

• Wound/ocular infection

• Symblepharon

• Corneal vascularization

Lopez-Garcia et al. [17]

2006

Prospective cohort

24

• Alkali

• Eye surgery

• Eye no surgery

• Dua’s grade III, IV

• Visual acuity

• Corneal ulceration

• Corneal vascularization

Singh et al. [18]

2008

Retrospective cohort

100

• Acid

• Alkali

• Chemical

• Eye surgery

• Eye no surgery

• Dua’s grade II-VI

• Visual acuity

• Corneal haze

• Symblepharon

• Corneal vascularization

Tandon et al. [19]

2011

Prospective, randomized trial

153

• Thermal

• Acid

• Alkali

• Eyelid surgery

• Eyelid no surgery

• Eye surgery

• Eye no surgery

• Dua’s grade II, III

• Time to management

• Visual acuity

• Corneal haze

• Epithelial defect area

• Time to epithelialization

• Limbal ischemia

• Symblepharon

• Corneal vascularization

Sharma et al. [20]

2015

Retrospective cohort

28

• Acid

• Alkali

• Eye surgery

• Eye no surgery

• Dua’s grade III-V

• Time to management

• Visual acuity

• Corneal haze

• Epithelial defect diameter

• Epithelial defect area

• Schirmer

• TBUT

• Time to epithelialization

• Healed epithelial defect

• Symblepharon

• Entropian

• Ectropian

• Corneal vascularization

Sharma et al. [21]

2016

Prospective, randomized trial

30

• Acid

• Alkali

• Eye surgery

• Eye no surgery

• Dua’s grade III-V

• Time to management

• Pain

• Corneal haze

• Epithelial defect diameter

• Epithelial defect area

• Schirmer

• TBUT

• Time to epithelialization

• Healed epithelial defect

• Limbal ischemia

• Symblepharon

• Corneal vascularization

Cabalag et al. [2]

2017

Retrospective cohort

326

• Thermal

• Chemical

• Eyelid surgery

• Eyelid no surgery

• Eye surgery

• Eye no surgery

• Eyelash surgery

• Eyelash no surgery

• SPT

• DPT

• FT

• Dua’s grade I, II

• %TBSA

• Time to management

• LOS

• Rate of intubation

• Inhalation injury

• Wound/ocular infection

• Eyelid contracture

• Corneal ulceration

• Vision loss

• Ectropian

  1. SPT superficial partial thickness, DPT deep partial thickness, FT full thickness, TBUT tear break-up time, LOS length of stay, %TBSA percent total body surface area