Author | Group | Sample size (n) | Surgery | Time to management (days) | Visual acuity | Pain (0–10) | Corneal haze | Epithelial defect diameter (mm) | Epithelial defect area (mm2) | Time to epithelialization (days) | Healed epithelial defect | Schirmer | TBUT (s) | Limbal ischemia (hours) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
I | F | I | F | I | F | I | F | I | F | I | F | |||||||||
Frank et al. [15] | Surgery | 22 | FTG | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Surgery | 10 | FTG, T | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
No surgery | 60 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Tamhane et al. [16] | Surgery | 20 | AMT | 2.5 ± 1 | 0.02 ± 0 | 0.3 ± 4 | 8.8 ± 2 | 2.5 ± 0.3 | – | – | – | – | 97 ± 39 | – | – | – | 7 ± 4 | 4 ± 4 | – | – |
No surgery | 24 | – | – | 0.1 ± 0.2 | 0.6 ± 0.4 | 8.6 ± 2 | 5.5 ± 1 | – | – | – | – | 61 ± 47 | – | – | – | 8 ± 4 | 5 ± 4 | – | – | |
Lopez-Garcia et al. [17] | Surgery | 12 | AMT | – | 0.2 ± 0.2 | 0.63 ± 0.2 | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
No surgery | 12 | – | – | 0.2 ± 0.2 | 0.4 ± 0.2 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Singh et al. [18] | Surgery | 50 | DALK | – | 0.3 ± 0.6 | 0.4 ± 0.2 | – | – | 3.7 ± 0.2 | 0.2 ± 0.5 | – | – | – | – | – | – | – | – | – | – |
No surgery | 50 | – | – | 0.3 ± 0 | 0.03 ± 0.5 | – | – | 3.7 ± 0.5 | 3.6 ± 0.5 | – | – | – | – | – | – | – | – | – | – | |
Tandon et al. [19] | Surgery | 38 | AMT | 5 ± 12 | 0.1 ± 0.3 | 0.3 ± 1 | – | – | 3 ± 2 | 1.3 ± 3 | – | – | 47 ± 80 | – | 27 ± 52 | – | – | – | 4.5 ± 3 | – |
No surgery | 36 | – | 7 ± 17 | 0.04 ± 1 | 0.2 ± 0.5 | – | – | 2.5 ± 3 | 0.5 ± 2 | – | – | 48 ± 116 | – | 35 ± 69 | – | – | – | 3 ± 4 | – | |
Surgery | 38 | AMT | 7.5 ± 12 | 0.005 ± 0 | 0.014 ± 0 | – | – | 1.5 ± 3 | 2 ± 3 | – | – | 114 ± 99 | – | 41 ± 65 | – | – | – | 9 ± 4 | – | |
No surgery | 41 | – | 7.5 ± 12 | 0.01 ± 0 | 0.01 ± 0 | – | – | 1.3 ± 3 | 2.5 ± 3 | – | – | 112 ± 106 | – | 56 ± 63 | – | – | – | 4.8 ± 4 | – | |
Sharma et al. [20] | Surgery | 18 | AMT | 7 ± 3 | 0.03 ± 0 | 0.5 ± 0.4 | – | – | 2.3 ± 1 | 0.4 ± 1 | 7.7 ± 1 | 1.7 ± 1 | 76 ± 27 | 1 ± 2 | 41 ± 29 | 18 | 13.3 ± 2 | 9.4 ± 1 | – | – |
No surgery | 20 | – | 6.6 ± 2 | 0.03 ± 0 | 0.3 ± 0.3 | – | – | 2.4 ± 1 | 1 ± 1 | 7.2 ± 2 | 3.2 ± 2 | 54 ± 22 | 6 ± 5 | 57.8 ± 29 | 17 | 13.7 ± 1 | 8.6 ± 1 | – | – | |
Sharma et al. [21] | Surgery | 15 | AMT | 4 ± 2 | – | – | 6.4 ± 1 | 2.4 ± 1 | 1.8 ± 1 | 1 ± 1 | 6 ± 2 | 0.2 ± 1 | 38 ± 22 | 0.4 ± 1 | 22 ± 10 | 14 | 21.2 ± 2 | 10.7 ± 2 | 7 ± 3 | 1.5 ± 2 |
No surgery | 15 | – | 4.2 ± 1 | – | 5.8 ± 1 | 2.2 ± 2 | 1.7 ± 1 | 1.1 ± 1 | 5.6 ± 2 | 2.6 ± 1 | 33 ± 20 | 6.8 ± 8 | 567 ± 15 | 10 | 18 ± 4 | 10.3 ± 4 | 6 ± 3 | 3.7 ± 3 | ||
Cabalag et al. [2] | Surgery | 49 | STG, FTG, T | 1 ± 2 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
No surgery | 277 | – | 0.6 ± 1 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |