Table 1 Study population with data on each patient
Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
|---|---|---|---|---|---|---|---|---|---|
Sex | M | F | F | M | M | M | M | M | |
Age (years) | 52 | 45 | 34 | 21 | 69 | 35 | 54 | 58 | |
Injury | |||||||||
Burn percentage of TBSA | 65 | 26 | 15 | 75 | 45 | 40 | 15 | 17 | |
Inhalation injury | No | Yes | Yes | Yes | Yes | Yes | Yes | Yes | |
ABSI score | 9 | 9 | 6 | 12 | 10 | 7 | 7 | 7 | |
R-Baux score | 117 | 88 | 66 | 113 | 131 | 92 | 86 | 92 | |
ARDS | |||||||||
Etiology: Immediate trauma | Yes | Yes | Yes | Yes | No | Yes | No | No | |
PaO2/FiO2 (mmHg) | 59 | 42 | 44 | 50 | 63 | 55 | 110 | 70 | |
Murray score | 3.7 | 3.8 | 3.5 | 3.5 | 3.7 | 3.3 | 3.3 | 3.3 | |
Measures prior to ECMO | |||||||||
Prone positioning | No | Yes | Yes | Yes | No | Yes | Yes | Yes | |
Nitric oxide inhalation | No | No | No | Yes | No | No | No | No | |
Recruitment maneuver | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | |
Neuromuscular blockade | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | |
Characteristics at ECMO onset | |||||||||
SOFA score | 19 | 13 | 9 | 13 | 19 | 10 | 10 | 6 | |
SAPS II score | 49 | 48 | 27 | 36 | 57 | 25 | 30 | 32 | |
Minute ventilation (l) | 12.1 | 8.5 | 7 | 10.1 | 8 | 10 | 9.9 | 12 | |
Tidal volume (ml) | 550 | 599 | 320 | 430 | 400 | 520 | 380 | 650 | |
Respiratory rate (/min) | 22 | 15 | 22 | 24 | 22 | 18 | 26 | 18 | |
PEEP (mmHg) | 13 | 20 | 11 | 11 | 12 | 15 | 14 | 12 | |
Plateau pressure (mmHg) | 42 | 40 | 35 | 35 | 35 | 35 | 30 | 30 | |
Compliance (ml/cm H2O) | 14 | 22 | 9.8 | 13.2 | 12.8 | 19.1 | 17.4 | 26.5 | |
Arterial pCO2 (mmHg) | 40 | 85 | 78 | 60 | 80 | 66 | 115 | 55 | |
Arterial pH | 7.38 | 7.23 | 7.24 | 7.28 | 7.3 | 7.3 | 7.07 | 7.43 | |
Arterial lactate (mmol/l) | 19.6 | 9.3 | 1.9 | 4.4 | 9.6 | 1.1 | 0.9 | 0.6 | |
Serum bilirubin (mg/dl) | 4.4 | 0.9 | 0.7 | 1.1 | 8.9 | 0.6 | 1.2 | 0.8 | |
Serum creatinine (mg/dl) | 1.8 | 1.4 | 0.8 | 1.9 | 3.4 | 0.9 | 1 | 0.9 | |
Outcome | |||||||||
ECMO duration (h) | 288 | 528 | 480 | 984 | 48 | 240 | 288 | 248 | |
Hospital stay (days) | 15 | 22 | 30 | 178 | 21 | 64 | 33 | 80 | |
ICU stay (days) | 15 | 22 | 20 | 178 | 21 | 34 | 33 | 80 | |
Renal replacement (days) | 15 | 0 | 4 | 76 | 4 | 0 | 0 | 0 | |
Mechanic ventilation (days) | 15 | 22 | 16 | 120 | 21 | 26 | 24 | 50 | |
Survival to discharge | No | No | Yes | Yes | No | Yes | Yes | Yes | |
Cause of death | Sepsis | Sepsis | – | – | Sepsis | – | – | – | |