| |
Patient
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
|---|
|
Sex
| |
M
|
F
|
F
|
M
|
M
|
M
|
M
|
M
|
|
Age (years)
| |
52
|
45
|
34
|
21
|
69
|
35
|
54
|
58
|
|
Injury
|
| |
Burn percentage of TBSA
|
65
|
26
|
15
|
75
|
45
|
40
|
15
|
17
|
| |
Inhalation injury
|
No
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
| |
ABSI score
|
9
|
9
|
6
|
12
|
10
|
7
|
7
|
7
|
| |
R-Baux score
|
117
|
88
|
66
|
113
|
131
|
92
|
86
|
92
|
|
ARDS
|
| |
Etiology: Immediate trauma
|
Yes
|
Yes
|
Yes
|
Yes
|
No
|
Yes
|
No
|
No
|
| |
PaO2/FiO2 (mmHg)
|
59
|
42
|
44
|
50
|
63
|
55
|
110
|
70
|
| |
Murray score
|
3.7
|
3.8
|
3.5
|
3.5
|
3.7
|
3.3
|
3.3
|
3.3
|
|
Measures prior to ECMO
|
| |
Prone positioning
|
No
|
Yes
|
Yes
|
Yes
|
No
|
Yes
|
Yes
|
Yes
|
| |
Nitric oxide inhalation
|
No
|
No
|
No
|
Yes
|
No
|
No
|
No
|
No
|
| |
Recruitment maneuver
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
| |
Neuromuscular blockade
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
|
Characteristics at ECMO onset
|
| |
SOFA score
|
19
|
13
|
9
|
13
|
19
|
10
|
10
|
6
|
| |
SAPS II score
|
49
|
48
|
27
|
36
|
57
|
25
|
30
|
32
|
| |
Minute ventilation (l)
|
12.1
|
8.5
|
7
|
10.1
|
8
|
10
|
9.9
|
12
|
| |
Tidal volume (ml)
|
550
|
599
|
320
|
430
|
400
|
520
|
380
|
650
|
| |
Respiratory rate (/min)
|
22
|
15
|
22
|
24
|
22
|
18
|
26
|
18
|
| |
PEEP (mmHg)
|
13
|
20
|
11
|
11
|
12
|
15
|
14
|
12
|
| |
Plateau pressure (mmHg)
|
42
|
40
|
35
|
35
|
35
|
35
|
30
|
30
|
| |
Compliance (ml/cm H2O)
|
14
|
22
|
9.8
|
13.2
|
12.8
|
19.1
|
17.4
|
26.5
|
| |
Arterial pCO2 (mmHg)
|
40
|
85
|
78
|
60
|
80
|
66
|
115
|
55
|
| |
Arterial pH
|
7.38
|
7.23
|
7.24
|
7.28
|
7.3
|
7.3
|
7.07
|
7.43
|
| |
Arterial lactate (mmol/l)
|
19.6
|
9.3
|
1.9
|
4.4
|
9.6
|
1.1
|
0.9
|
0.6
|
| |
Serum bilirubin (mg/dl)
|
4.4
|
0.9
|
0.7
|
1.1
|
8.9
|
0.6
|
1.2
|
0.8
|
| |
Serum creatinine (mg/dl)
|
1.8
|
1.4
|
0.8
|
1.9
|
3.4
|
0.9
|
1
|
0.9
|
|
Outcome
|
| |
ECMO duration (h)
|
288
|
528
|
480
|
984
|
48
|
240
|
288
|
248
|
| |
Hospital stay (days)
|
15
|
22
|
30
|
178
|
21
|
64
|
33
|
80
|
| |
ICU stay (days)
|
15
|
22
|
20
|
178
|
21
|
34
|
33
|
80
|
| |
Renal replacement (days)
|
15
|
0
|
4
|
76
|
4
|
0
|
0
|
0
|
| |
Mechanic ventilation (days)
|
15
|
22
|
16
|
120
|
21
|
26
|
24
|
50
|
| |
Survival to discharge
|
No
|
No
|
Yes
|
Yes
|
No
|
Yes
|
Yes
|
Yes
|
| |
Cause of death
|
Sepsis
|
Sepsis
|
–
|
–
|
Sepsis
|
–
|
–
|
–
|
- TBSA total body surface area, ABSI Abbreviated Burn Severity Index, SOFA Sequential Organ Failure Assessment, SAPS II Simplified Acute Physiology Score II, PEEP positive end-expiratory pressure, ICU intensive care unit, ARDS acute respiratory distress syndrome, ECMO extracorporeal membrane oxygenation, M male, F famale