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Fig. 1 | Burns & Trauma

Fig. 1

From: Neutralization of interleukin-17A alleviates burn-induced intestinal barrier disruption via reducing pro-inflammatory cytokines in a mouse model

Fig. 1

Microscopic appearance of intestine barrier disruption and zonula occludens-1 (ZO-1) alteration induced by burn injury. Ileal sections were stained with hematoxylin and eosin (H&E) (a, b, 200x), and mucosa lensions were scored in both groups (c). Representative immunofluorescent images depicting membrane localization of ZO-1 in sham group (d-f), and burn group (g-i), red staining indicates ZO-1, and blue staining indicates nuclei (400x). Intestinal permeability was measured by fluorescein isothiocyanate (FITC)-dextran levels and is expressed as optical density (OD) value (mean ± standard error of the mean (SEM)) (j). n = 5 per group.***p < 0.001. DAPI 4′,6-diamidino-2-phenylindole

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Burns & Trauma

ISSN: 2321-3876

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