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Table 2: Whole-blood GSH and plasma cysteine kinetics in sham burn and burned rabbits

From: Burn injury differentially alters whole-blood and organ glutathione synthesis rates: An experimental model

  Sham burn Burned
Body weight (kg) 2.7 ± 0.1 2.5 ± 0.1
Cysteine flux (μmol/kg/h) 29.3 ± 5.1 65.6 ± 8.9
Increment of 13C-cysteine-GSH enrichment (molar ratio excess/min) 2.09 × 10−4 1.15 × 10−4†
FSRwb,gsh (per day) 0.46 ± 0.04 0.38 ± 0.02¥
Blood GSH concentration (μmol/l) 1486.0 ± 118.6 1263.8 ± 78.7§
Blood GSH synthesis rate (ASRwb,gsh, μmol/min/l) 666.7 ± 58.2 486.9 ± 41.6
  1. *Data are presented as Mean±SEM, sham burn n=7, burned n=6
  2. Significantly different from sham burn animals, P<0.001 by unpaired t-test (equal variance)
  3. ¥Significantly different from sham burn animals, P<0.05 by unpaired t-test by Wilcox ranking test
  4. §Significantly different from sham burn animals, P=0.054 by unpaired t-test (equal variance)
  5. Significantly different from sham burn animals, P<0.01 by Wilcox ranking test