Expression of kidney injury molecule-1 (KIM-1) in mouse kidney in each group. MG53 immunohistochemical staining in mouse kidney tissues from each group (×400). (a) Endogenous MG53 is expressed in control muscle. (b) There is no MG53 expression in renal tissues. (c) Exogenous rhMG53 was not detected in renal tissue in the BSA-treated group. (d) Exogenous rhMG53 was detected in epithelial cells located in the (e) renal cortex and (f) renal medulla. Positive cells are indicated by the arrow. Scale bar denotes 100 µm.