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Figure 1 | Burns & Trauma

Figure 1

From: Role of CD8+ regulatory T cells in organ transplantation

Figure 1

CD8+ regulatory T cell (Treg) phenotypes. Natural CD8+CD122+ Tregs are CD44highCD62L+CD127+ and partially PD-1-positive (PD-1+/−) but are FoxP3-negative. Natural CD8+CD28 Tregs (nTreg) are CD44lowCD62L+ but GITR-CTLA4-FoxP3; whereas, induced CD8+CD28 Tregs (iTreg) are CD44highCD62L+, but GITR+CTLA4+FoxP3+. CD8+CD103+ Tregs are CD44lowCD62LhighFoxP3+. GITR = Glucocorticoid-induced tumor necrosis factor receptor-related protein, CTLA4 = cytotoxic T-cell antigen 4.

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