Ventilation strategies in burn intensive care: A retrospective observational study

Burns & Trauma

Table 2 Comparison of ventilation parameters in two time-separated burn intensive care unit cohorts

Parameter	2005/06 cohort	2010/2011 cohort	P-value
Ventilator rate (breaths·min⁻¹)	17.2 (15.1–19.4)	17.7 (16.0–19.3)	0.747
Spontaneous rate (breaths·min⁻¹)	17.2 (12.2–22.2)	17.0 (13.0–21.0)	0.944
Ventilator tidal volume (ml/kg)	8.32 (7.67–9.10)	7.96 (6.30–9.62)	0.624
Spontaneous tidal volume (ml/kg)	8.45 (6.69–10.2)	8.45 (6.63–10.3)	0.995
Minute volume (L·min⁻¹)	11.9 (9.28–14.1)	10.3 (8.17–12.5)	0.373
Inspiratory pressure* (kPa)	2.78 (2.21–3.35)	2.74 (2.31–3.16)	0.884
ASB† pressure (kPa)	1.60 (1.21–1.98)	1.20 (1.08–1.31)	0.034
Peak airway pressure* (kPa)	2.52 (2.14–2.90)	2.63 (2.00–2.73)	0.518
Positive end expiratory pressure (kPa)	0.70 (0.59–0.81)	0.75 (0.65–0.86)	0.479
Inspired O₂ concentration (%)	46.9 (37.4–56.2)	40.2 (35.1–45.3)	0.184

Values are mean (95% confidence interval): P-value calculated with two-tailed t-test. *Inspiratory pressure applies during pressure controlled ventilation mode only. Peak airway pressure applies during volume controlled and spontaneous ventilation modes only. ^†ASB = Assisted spontaneous breathing.

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