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Table 1: Twenty-one commonly secreted proteins from NSFs and HSFs

From: Comparative proteomic analysis of extracellular matrix proteins secreted by hypertrophic scar with normal skin fibroblasts

Protein definition

Accession number

pI

MW

Adipocyte enhancer-binding protein 1

IPI00745313

5.05

130,929

Collagen α-1(I)

IPI00297646

5.61

138,912

Collagen α-1(VI)

IPI00291136

5.26

108,530

Collagen α-3(VI)

IPI00022200

6.27

343,671

Collagen α-1(XII)

IPI00329573

5.38

333,148

Type IV collagenase

IPI00027780

5.26

73,883

Complement C1r subcomponent

IPI00296165

5.89

80,174

Complement C3

IPI00783987

6.02

187,149

EGF-containing fibulin-like extracellular matrix protein 1

IPI00029658

4.95

54,641

Fibronectin

IPI00414283

5.53

256,513

Galectin-3-binding protein

IPI00023673

5.13

65,331

Glia-derived nexin

IPI00009890

9.35

44,003

Laminin subunit α-4

IPI00329482

5.90

202,529

Laminin subunit γ-1

IPI00298281

5.01

177,608

γ-2-macroglobulin

IPI00478003

6.00

163,279

Pappalysin-1

IPI00001869

5.78

181,142

Pentraxin-related protein PTX3

IPI00029568

4.90

42,020

Plasma protease C1 inhibitor

IPI00291866

6.09

55,155

Plasminogen activator inhibitor 1

IPI00007118

6.67

45,060

Sulfhydryl oxidase 1

IPI00003590

9.13

82,578

Transforming growth factor-β-induced protein ig-h3

IPI00018219

7.62

74,681

  1. NSF = Normal skin fibroblast, HSF = Hypertrophic scar fibroblasts, MW = Molecular weight, pI = Isoelectric point, EGF = Epidermal growth factor