|
Biomarkers of post-traumatic sepsis
|
Predictive value
|
Study
|
|---|
|
PCT
|
Yes
|
[27,28,30–34]
|
|
CRP
|
No
|
[4,28,30–32,40–43]
|
|
IL-6
|
Controversial
|
Yes [31,32]
|
| | |
No [42,43,47–50]
|
|
IL-10
|
Yes
|
[4, 53–56]
|
|
Neopterin
|
No
|
[42, 58–60]
|
|
PSP/reg
|
Yes
|
[32]
|
|
IL-1
|
Yes
|
[55]
|
|
NT-proCNP
|
Yes
|
[66]
|
|
PMNE
|
Controversial
|
Yes [47, 59]
|
| | |
No [42, 43]
|
|
Lactate clearance
|
Yes
|
[31, 68]
|
|
IL-18
|
Yes
|
[58]
|
|
mHLA-DR
|
Yes
|
[72, 73]
|
|
TNF-α
|
No
|
[60]
|
|
TLR-9
|
Yes
|
[74]
|
|
PMN CD11b
|
Yes
|
[49]
|
|
sFAS
|
Yes
|
[47]
|
|
Gc-globulin
|
Yes
|
[75]
|
|
s-TM
|
Yes
|
[77]
|
|
kynurenine values and kynureninetryptophan ratio
|
Yes
|
[76]
|
- PCT = Procalcitonin, CRP = C-reactive protein, IL = Interleukin, PSP/reg = Pancreatic stone protein/regenerating protein, NT-proCNP = Amino-terminal pro-peptide, PMNE = Polymorphonuclear elastase, mHLA-DR = Monocyte Human Leukocyte Antigen DR, TNF-α = Tumor necrosis factor α, TLR-9 = Toll-like receptor-9, PMN CD11b = Polymorphonuclear cluster of differentiation 11b, sFAS = Soluble FAS, Gc-globulin = Group-specific component globulin, s-TM = Soluble thrombomodulin
