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Table 1: Evaluation of biomarkers of post-traumatic sepsis

From: Prediction of sepsis in trauma patients

Biomarkers of post-traumatic sepsis Predictive value Study
PCT Yes [27,28,3034]
CRP No [4,28,3032,4043]
IL-6 Controversial Yes [31,32]
   No [42,43,4750]
IL-10 Yes [4, 5356]
Neopterin No [42, 5860]
PSP/reg Yes [32]
IL-1 Yes [55]
NT-proCNP Yes [66]
PMNE Controversial Yes [47, 59]
   No [42, 43]
Lactate clearance Yes [31, 68]
IL-18 Yes [58]
mHLA-DR Yes [72, 73]
TNF-α No [60]
TLR-9 Yes [74]
PMN CD11b Yes [49]
sFAS Yes [47]
Gc-globulin Yes [75]
s-TM Yes [77]
kynurenine values and kynureninetryptophan ratio Yes [76]
  1. PCT = Procalcitonin, CRP = C-reactive protein, IL = Interleukin, PSP/reg = Pancreatic stone protein/regenerating protein, NT-proCNP = Amino-terminal pro-peptide, PMNE = Polymorphonuclear elastase, mHLA-DR = Monocyte Human Leukocyte Antigen DR, TNF-α = Tumor necrosis factor α, TLR-9 = Toll-like receptor-9, PMN CD11b = Polymorphonuclear cluster of differentiation 11b, sFAS = Soluble FAS, Gc-globulin = Group-specific component globulin, s-TM = Soluble thrombomodulin