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Table 1: Evaluation of biomarkers of post-traumatic sepsis

From: Prediction of sepsis in trauma patients

Biomarkers of post-traumatic sepsis

Predictive value

Study

PCT

Yes

[27,28,30–34]

CRP

No

[4,28,30–32,40–43]

IL-6

Controversial

Yes [31,32]

  

No [42,43,47–50]

IL-10

Yes

[4, 53–56]

Neopterin

No

[42, 58–60]

PSP/reg

Yes

[32]

IL-1

Yes

[55]

NT-proCNP

Yes

[66]

PMNE

Controversial

Yes [47, 59]

  

No [42, 43]

Lactate clearance

Yes

[31, 68]

IL-18

Yes

[58]

mHLA-DR

Yes

[72, 73]

TNF-α

No

[60]

TLR-9

Yes

[74]

PMN CD11b

Yes

[49]

sFAS

Yes

[47]

Gc-globulin

Yes

[75]

s-TM

Yes

[77]

kynurenine values and kynureninetryptophan ratio

Yes

[76]

  1. PCT = Procalcitonin, CRP = C-reactive protein, IL = Interleukin, PSP/reg = Pancreatic stone protein/regenerating protein, NT-proCNP = Amino-terminal pro-peptide, PMNE = Polymorphonuclear elastase, mHLA-DR = Monocyte Human Leukocyte Antigen DR, TNF-α = Tumor necrosis factor α, TLR-9 = Toll-like receptor-9, PMN CD11b = Polymorphonuclear cluster of differentiation 11b, sFAS = Soluble FAS, Gc-globulin = Group-specific component globulin, s-TM = Soluble thrombomodulin