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Table 2: A few examples of hydrogel-based dressings and regenerative templates investigated in recent literature for the treatment of partial- and full-thickness burns, respectively

From: Polymeric hydrogels for burn wound care: Advanced skin wound dressings and regenerative templates

Burn depth

Hydrogel precursor(s)

Additional component(s)

Reference(s)

Partial-thickness

AMPS/PEGDA

—

[20]

 

AMPS

Silver nanoparticles

[27],[36],[37]

 

Chitin

ZnO nanoparticles

[29],[30]

 

Chitosan

—

[15],[38]

 

Keratin

—

[39]

 

Laponite®/alginate (*)

Mafenide

[40]

 

PVA/chitosan

Silver sulfadiazine

[28],[41]

 

PVA

Silver nanoparticles

[42]

 

PVA/lysine/vanillin

—

[43]

 

PVP/PEG

Honey

[44]

 

PVP/PEG

Sea cucumber

[45]

 

Self-assembling peptides

—

[46],[47]

Full-thickness

Chitosan

—

[25]

 

Chitosan/collagen

Lysostaphin

[31]

 

Collagen/PEG/fibrin

—

[48]

 

Dextran/PEGDA

—

[49]

 

Dextran

Chitosan microparticles with EGF and VEGF

[50]

 

Hyaluronan

—

[51]

 

Hyaluronan/gelatin/PEGDA (Extracel®)

—

[52]

  1. AMPS = 2-acrylamido-2-methylpropane sulfonic acid sodium salt, PEGDA = polyethylene glycol diacrylate, PVA = Polyvinyl alcohol, PVP = Polyvinyl pyrrolidone, PEG = polyethylene glycol, EGF = epidermal growth factor, VEGF = vascular endothelial growth factor, (*) Laponite is a gel forming clay