Burns & Trauma

Featured article: Synthesis of GO-QAS nanocomposite with synergistic antibacterial activity to promote infected wound healing

The GO-QAS nanocomposite exhibits excellent biocompatibility and synergistic antibacterial ability against multidrug resistant bacteria through not only mechanical membrane perturbation, including wrapping, bacterial membrane insertion, and bacterial membrane perforation, but also oxidative stress induction. Notably, GO-QAS topically applied on infected wounds maintained highly efficient antibacterial activity and accelerated the healing process of infected wounds by promoting re-epithelialization and granulation tissue formation. In the future, GO-QAS nanocomposite could be applied as a promising antimicrobial agent for infected wound management and antibacterial wound dressing synthesis.