An objective measure for the assessment and management of fluid shifts in acute major burns

Burns & Trauma

Table 4 Predictor variable effects on whole-body BIS variables for determining the effect of Acticoat™

BIS variable	Covariate	Co-efficient	Confidence intervals		p value
BIS variable	Covariate	Co-efficient	Lower	Upper	p value
R₀ (ohms)	Acticoat™	− 17.42	− 39.35	4.52	0.12
	% TBSA	− 1.07	− 2.75	0.61	0.21
	Acticoat™#% TBSA	− 4.68	− 5.37	− 3.98	< 0.01*
	Initial TBF (L)	− 5.71	− 8.32	− 3.09	< 0.01*
R_i (ohms)	Acticoat™	− 182.22	− 265.27	− 99.16	< 0.01*
	% TBSA	6.50	− 3.45	16.46	0.20
	Acticoat™#% TBSA	− 17.98	− 20.61	− 15.36	< 0.01*
	Initial TBF (L)	− 32.52	− 48.16	− 16.87	< 0.01*
R_inf (ohms)	Acticoat™	− 23.87	− 38.57	− 9.17	< 0.01*
	% TBSA	− 0.01	− 1.33	1.32	0.99
	Acticoat™#% TBSA	− 3.96	− 4.42	− 3.49	< 0.01*
	Initial TBF (L)	− 5.30	− 7.37	− 3.23	< 0.01*
ECF (L)	Acticoat™	− 36.23	− 41.91	− 30.55	< 0.01*
	% TBSA	− 0.04	− 0.31	0.23	0.76
	Acticoat™#% TBSA	1.86	1.68	2.04	< 0.01*
	Initial TBF (L)	0.93	0.53	1.33	< 0.01*
ICF (L)	Acticoat™	− 31.00	− 36.07	− 25.92	< 0.01*
	% TBSA	− 0.15	− 0.36	0.07	0.18
	Acticoat™#% TBSA	2.01	1.85	2.17	< 0.01*
	Initial TBF (L)	1.08	0.77	1.40	< 0.01*
TBF (L)	Acticoat™	− 67.23	− 77.13	− 57.32	< 0.01*
	% TBSA	− 0.19	− 0.63	0.25	0.40
	Acticoat™#% TBSA	3.87	3.55	4.18	< 0.01*
	Initial TBF (L)	2.02	1.36	2.67	< 0.01*

Acticoat™ is in reference to an open wound
R₀ resistance at zero frequency, R_i intracellular resistance, R_inf resistance at infinite frequency, ECF extracellular fluid, ICF intracellular fluid, TBF total body fluid, TBSA total body surface area, BIS bioimpedance spectroscopy
*p ≤ 0.05
#Interaction term

ISSN: 2321-3876