Soybean-based pastes in the PTFE chamber wound model after 6 days of implantation. (a–c) Control wound with applied split-thickness autologous graft, (d–f) non-cross-linked paste of Figure 1a, (g–i) cross-linked paste of Figure 1b. (a, d, g) Picrosirius staining, (b, e, h) Birefringence microscopy, (c, f, i) hematoxylin and eosin staining at high magnification showing polymorphonucleate infiltrates degrading paste granules. Asterisks indicate soybean-based paste granules. Scale bar: a, d and g, 200 µm;m; b, e and h, 1000 µm;m; c and f, 100 µm;m; i, 20 µm;m.