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Fig. 2 | Burns & Trauma

Fig. 2

From: The molecular basis of hypertrophic scars

Fig. 2

The roles of monocytes and polarized macrophages in HTS formation. We hypothesize that monocytes in the blood are recruited to the injured site via the SDF-1/CXCR4 signaling pathway and differentiate into polarized macrophages. The polarized M1 and M2 macrophages then exert their functions via various signaling pathways and involve in wound healing and HTS formation

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